Everton boss Sam Allardyce will miss Thursday’s Europa League match at Apollon Limassol in Cyprus because of a “pre-arranged medical appointment”.
Allardyce, 63, was appointed as Ronald Koeman’s successor on 30 November and his only game in charge so far was Saturday’s 2-0 win over Huddersfield.
In Allardyce’s absence, Ferguson and Shakespeare, who was in charge for part of Leicester’s Champions League run last term, are set to take charge of an inexperienced XI.
Everton’s dismal Europa League campaign has seen them pick up just one point from their five group matches, against Apollon at Goodison Park in September, in the worst record of any English club in the competition’s history.
Their concluding clash in Cyprus is a dead rubber for both teams as the hosts, with just three points to their credit, cannot qualify for the last 32 either.